Saturday, May 30, 2009

Triglycerides for Diabetic Experience Worsening Neuropathy

Highest levels of triglycerides were significantly more likely to experience worsening neuropathy over the course of one year, regardless of how long patients had the disease or how controlled it was.

Diabetic neuropathy affects around 60 percent of the 23 million people in the United States who have diabetes. It is a complication in both type 1 and type 2 diabetes.

Diabetic neuropathies are neuropathic disorders that are associated with diabetes mellitus. These conditions are thought to result from diabetic microvascular injury involving small blood vessels that supply nerves that allow you to feel sensations such as pain.

University of Michigan and Wayne State University researchers analyzed data from 427 diabetes patients with neuropathy, a condition in which nerves are damaged or lost with resulting numbness, tingling and pain, often in the hands, arms, legs and feet. The data revealed that if a patient had elevated triglycerides, he or she was significantly more likely to experience worsening neuropathy over a period of one year. Other factors, such as higher levels of other fats in the blood or of blood glucose, did not turn out to be significant.

Triglycerides are measured as part of a blood test that measures your cholesterol. Normal triglyceride levels are below 150. High levels are 200 or above.

When triglyceride levels are high, it is not clear whether these high levels directly increase your risk for heart disease. But high triglycerides are often part of a group of conditions called metabolic syndrome.

Metabolic syndrome is the combination of high blood pressure, high blood sugar, too much fat around the waist, low HDL ("good") cholesterol, and high triglycerides. This syndrome does increase your risk for heart disease as well as for diabetes and stroke.

People can reduce blood triglyceride levels with the same measures that reduce cholesterol levels: by avoiding harmful fats in the diet and exercising regularly.

Source : Several blog and newsfeed

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